ITA Serie A Betting Markets & Odds

Italy’s Serie A is one of the best leagues in Europe, with some historic giants clashing every week. With the likes of Juventus, the two Milan teams, Napoli, Lazio, Roma and more, there are many exciting betting opportunities as the season takes shape.  

Explore the latest Serie A betting odds and discover your options for betting on Italy’s top flight at Betano Sportsbook, including outright, pre-match, and in-play betting markets.

Seria A Outright betting is the most popular Serie A market, requiring you to pick the eventual winner of the competition. Here are the different ways you can bet on the action in Italy’s top flight throughout the 2025/26 campaign:

Outright Betting

Serie A outright betting is hugely popular at Betano, with many people backing the big boys to secure the Scudetto at the end of the season. Back Napoli, Inter, Milan, Roma, or Juventus to win the title, or back outsiders like Fiorentina or even Como to shock the country with a title challenge.

We also offer you the chance to bet on the teams you think will finish in the top four positions in Serie A, securing Champions League qualification at the end of the long and gruelling season.

Match Betting

There are 380 matches during the Serie A season, creating ample match betting options. You can bet on the outcome of multiple games throughout the campaign, with handicap betting letting you back heavy favourites at enhanced odds. You can also bet on the total number of goals scored in a particular match, over or under a specific amount. The both teams to score market is also an excellent option for Serie A fans.

The Serie A Top Scorer

The Paolo Rossi Award, handed to Serie A’s top goalscorer, is another popular market to bet on for the 2025/26 season. Atalanta’s Mateo Retegui finished the 2024/25 campaign with 25 goals, winning the award before securing a big-money transfer to Al-Qadsiah in Saudi Arabia.

Inter’s Lautaro Martinez could be a good shout for the award this season, while Napoli’s Romelu Lukaku will look to improve on his fourteen goals last season, and may well end his second season in Naples with the Paolo Rossi Award.

Transfer Market Betting

Here at Betano, you can bet on several events during the course of the 2025/26 Serie A season. We even publish transfer odds about specific players and their likely destinations. You can also access transfer specials, which are focused on individuals and the clubs they’ve been linked with during a summer or winter window. Betting on this market requires detailed knowledge and insight, which can be sourced through official club news sites and reputable social media channels.

Napoli won their second title in three seasons in 2024/25 and their fourth Scudetto overall. Under popular manager Antonio Conte, the Naples club secured Kevin De Bruyne's signature in the summer, which will pair the legendary Belgian midfielder with his Red Devils teammate, Romelu Lukaku.

Scott McTominay will also likely continue his brilliant form, which earned him the nickname “the King of Naples” last season. Undoubtedly, Napoli will be the team to beat again this season.

They will likely be challenged by Inter, Milan, and Juventus, who have all won the Scudetto in recent years. Here’s a run-through of the ten most recent winners of the Serie A title:

Defending champions Napoli are the pre-season favourites to win Serie A in 2025/26. Antonio Conte has strengthened his team and will look to secure the club’s third title in four years, ensuring the title remains in southern Italy.

2024/25 UEFA Champions League finalists Inter start as second favourites to win the Scudetto. Inter had a brilliant season last year, despite the humiliation they suffered at the hands of PSG in the Champions League final. They will embark on this season under a new coach, Christian Chivu, after Simone Inzaghi took over at Al-Hilal in the summer.

The Old Lady, Juventus, begin the campaign next in line to win the title. Though they dominated in the 2010s, Juve haven’t won the title since 2019/20, and their fans will be hoping that Igor Tudor’s squad has enough to go the distance this time around.

AC Milan, Roma, and Atalanta are the other teams most likely to mount a Serie A title challenge during the 2025/26 season.

Pre-season is arguably the ideal time to bet on the next Serie A winner and top scorer, with the odds for the most likely outcomes in these markets expected to shorten as the campaign gets underway.

That said, you can back your Serie A winner at any time of the season from your Betano account while accessing pre-match and in-play markets for Italy’s top flight.

However you choose to wager on Serie A, we encourage you to gamble responsibly. This requires you to set a realistic bankroll that covers a finite period, which can be managed using customisable deposit limits and timeouts. You can access these tools and more through our comprehensive Safer Gambling Portal.